How healthy cells become cancerous? The process of cell division, whether in regular or cancer cells, takes place through the cell cycle. The cell cycle goes from the resting phase, through the active growth phases, to mitosis (division). (1*, 2*, 3*)
What is cancer?
Cancer is a horrifying disease and one of the common causes of death in the world. Every year, thousands of people are diagnosed with cancer, and many die from the disease. That makes us wonder how this lethal disease, rather a group of diseases, develops? To answer this
we need to understand the difference between a healthy cell and a sick or cancerous cell.
The battle against cancer can be very tough indeed. Cancer is a tumor or a group of rogue cells causing all sorts of troubles in the body.
The invasion of cancerous cells can cause malignant growth into areas of normal tissue. Cancerous cells are known as malignant neoplasia.
This term refers to a tissue that has cancerous characteristics. Common types of malignancies include leukemia, lymphoma, myeloma, rectal cancer, breast cancer, nasal cavity cancer, colon cancer, gall bladder cancer, melanoma, skin cancer, and colon cancer.
Some forms of cancer can start in any of these issues; however, it begins in the neoplastic form.
Difference between a normal cell and a cancer cell
The difference between a normal cell and a cancer cell is the size and number of chromosomes they carry. Cancer cells, on the other hand, have lost most or all of their chromosomes.
This makes them very different. One characteristic that makes cancer cells different from normal cells is that they divide quickly. The rate of division of a cancer cell is ten times faster than that of a normal cell.
Cancerous cells also look differently. They usually begin to form tumors which will then fill with blood. Cancerous cells have also been known to secrete chemicals that are distinct from those of normal cells.
Cancerous cells also appear to be able to live longer than normal cells. Studies have suggested that some cancerous cells can live up to 100 years.
There are several characteristics of cancer that make it different from normal cells:
- Cancer cells form tumors in the lining of the organs that they are trying to invade.
- They often attack the surrounding healthy tissue before going after cancer.
- They secrete chemicals that are distinct from those of normal cells.
Cancer cells appear to be better at invading and attacking tissues. However, there are also differences between a cancer cell and a normal cell.
Normal cells keep trying to repair themselves and keep getting new cells from another part of the body. In a cancer cell, the same thing happens, but it never stops, and it never gets new cells.
A cancer cell is a problem that always needs attention. To keep fighting the fight against the disease, the cancer cell has to attack new cells daily.
How healthy cells become cancerous?
Cancers that have an underlying cause: There are six reasons why normal cells get cancerous, which include radiation and chronic diseases. The sixth reason is due to genetic predisposition.
Now, I am going to explain the cancer reasons and how they contribute to the growth of cancerous tumors.
Gene abnormalities are found in both standard and cancerous cells. A common exception found in cancer is copy number variations, where some genes get altered and cause cancer.
In normal cells, the number of genes that get altered is generally relatively fewer, and expected growth is usually very regular.
However, in the case of mutation, copy number variations can cause abnormal development. It is for this reason that many normal cells turn cancerous.
Exposure to toxins
Toxins and chemicals interfere with the normal growth process. These substances either increase the rate of growth or change the type of cells that are present.
Some chemicals and toxins have been known to cause spontaneous mutations, which are also known as cancer. Free radicals and inflammatory agents can cause deregulation of cell metabolism.
These factors compromise the functions of normal cells and lead to malignant growth.
Exposure to environmental toxins can also cause cancer since the body cannot get rid of toxins. Cancerous tumors can be caused by toxic substances either directly or indirectly. Direct exposure to carcinogens such as cigarette smoke, air pollution, ultraviolet light, drugs, radiation, and chemicals can cause cancer.
Indirect effects include chronic inflammation, overgrowth of malignant cells, accumulation of abnormal tissue, and genetic abnormalities. Environmental Factors One of the reasons why normal cells become cancerous is due to external factors.
These may include exposure to certain chemicals, pesticides, or pesticides used by farming, forestry, and petrochemical industries.
Pollution from factories may be another environmental factor that affects cells around us. We also inherit our skin color, type of hair, and other traits from our parents, affecting our health and chance of developing cancer.
Mutation in DNA
Cancer has many causes; however, the most common cause is. Mutations happen when DNA is passed from one cell to another, changing its structure or function.
This mutation is commonly referred to as inheritance. It is also possible for cancer to spread from a single cell through a blood cell or a tissue.
When cancer spreads to neighboring cells or from a cell and tissue in which it originally formed, the condition is referred to as metastasis.
Human genes are responsible for determining the shape and structure of normal cells and tissues. Any alteration in DNA, whether through disease or natural process, can cause drastic changes to the cells.
Any modifications in DNA may lead to cancer. Cancer cells require glucose for energy. Cancer can spread rapidly through contact with the air and communication with the surrounding tissue.
People live hectic lives with very little time to eat correctly and exercise. Cancer is more likely in people with diets high in fat, sugar, and processed foods.
Processed foods contain chemicals that mimic hormones, which may be responsible for encouraging cancer growth. Obesity, especially in youth, is another lifestyle factor that can increase the risk of developing cancer.
Many things can contribute to an elevated stress level. Cancer is more likely in frayed people. Changing your routine may help minimize the chances of you getting the disease.
Cancer is one of the most dreaded diseases in the world. It is one of the most fatal when it affects vital organs like the heart, brain, and lung. Cancer has no boundaries; it has no specific stage, and it targets any part of the body from the head to the toes.
How healthy cells become cancerous? So, the cancerous cells can destroy the usual composure of life drastically. If you would not change your lifestyle and act in situations, cancer’s pain will be immense. You can save yourself from these cell and gene abnormalities through a healthy lifestyle and prevention from the toxins around you.
Written by Muddassir Abdur Rub M. D.